Generic Colospa

Common use

Colospa is a musculotropic antispasmodic medication used in the treatment of irritable bowel syndrome. It is also indicated for treatment of gastrointestinal spasm caused by a primal organic disorder. Mechanism of its action consists in relaxing of gut muscles at the cellular level. Colospa blocks transfer of Na+ through fast channels of myocyte into th cell and also inhibits calcium-depot replenishment, thus it performs a dual effect on bowels causing them to relax. It does not affect muscles of bronchi or uterus. No significant inhibition of normal peristalsis has been observed. This drug is used to treat a spasm of gastrointestinal organs (including due to organic disease), intestinal colic, biliary colic, irritable bowel syndrome (symptomatic treatment of pain and cramps, and intestinal disorders and discomfort) in adults.



Dosage and directions

Recommended daily dose of Colospa is 135 mg (1 tablet) 3 times daily, preferably before meals. Gradually the dosage may be reduced when the desired effect has been obtained.





Precautions

In pregnant patients Colospa is possible to use when expected benefit of treatment exceeds potential risk for the unborn baby. Avoid driving or be specially cautious when you need to drive or operate any machinery and mechanisms due to the possible dizziness caused by Colospa. Carefulness should be exercised in patients with paralytic ileus which is obstruction caused by failure of function of the intestine. This medicine is not recommended to treat children under 10 years of age. Discuss with your doctor if you suffer from inactivity of the bowel or allergic to any sugars before to take Colospa.



Contraindications

Hypersensitivity, porphyria.



Possible side effect

Any medication may affect different people individually, symptoms of allergy (hives, rash, swelling of face) may appear. If you need more information about any other possible risks associated with Colospa, you should consult your doctor or pharmacist.



Drug interaction

This medicine is not known to interact with other medication.



Missed dose

If you missed a dose take the medication as soon as you remember. If it is almost time of your next dose just skip its intake and return to your regular schedule.



Overdose

Overdose symptoms are unknown or may appear as over excitation of the central nervous system. Anyway if consider that you took too much of this medication consult your doctor, as you may need medical help.



Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Clinical Verification

Last Clinically Updated: August 15, 2026

Written By

Dr. Elena Vance, PharmD

Clinical Specialist in Neuropharmacology

Fact Checked By

Marcus Thorne, MS

Biomedical Data & FDA Label Verification

Medically Reviewed By

Dr. Arthur Campbell, MD

Board-Certified Psychiatrist (ABPN)