Generic Compazine

Common use

Compazine is an anti-psychotic medication which used to treat psychotic disorders such as schizophrenia. Also Compazine used to control severe nausea and vomiting and to treat anxiety. Compazine changes the actions of chemicals in your brain. Compazine is usually used as tranquilizer and antipsychotic drug.



Dosage and direction

Take it orally with a full glass of water, with or without food or milk.

The recommended dose for adults depend from type of disease:

To Control Severe Nausea and Vomiting

The usual dosage is one 5-milligram or 10-milligram tablet 3 or 4 times a day.

For Non-psychotic Anxiety

The usual dose is 5 milligrams, taken 3 or 4 times a day.

Relatively Mild Schizophrenia

The usual dose is 5 or 10 milligrams, taken 3 or 4 times daily.

Moderate to Severe Schizophrenia

Dosages usually start at 10 milligrams, taken 3 or 4 times a day.

More Severe Schizophrenia

Dosages may range from 100 to 150 milligrams per day.

The recommended dose for children also depends from type of disease, weight and their age:

Children under 2 years of age or weighing less than 20 pounds should not be given Compazine.

For Severe Nausea and Vomiting

An oral of Compazine is usually not needed for more than 1 day.

Children 20 to 29 Pounds

The common dose is 2-0.5 mg 1 or 2 times daily. Do not give over 7.5 mg daily.

Children 30 to 39 Pounds

The usual dose is 2-0.5 mg 2 or 3 times daily. Do not give over 10 mg daily.

Children 40 to 85 Pounds

The usual dose is 2-0.5 mg 3 times daily, or 5 mg 2 times daily. Do not give over 15 mg.

For Psychotic Disorders

Children 2 to 5 Years Old

The starting oral or rectal dose is 2-0.5 mg 2 or 3 times daily. Do not give over 10 mg the first day and 20 mg thereafter.

Children 6 to 12 Years Old

The starting oral or rectal dose is 2-0.5 mg 2 or 3 times daily. Do not give over 10 mg the first day and 25 mg thereafter.

The recommendation for older adults:

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.





Precautions

Use Compazine with cautions in people with hepatic or renal disease, glaucoma, prostatic hypertrophy, severe asthma, prolonged use, cardiovascular disease, epilepsy. Do not use in children under 5 years age. Compazine should not be used during pregnancy, becoming pregnant or lactating without doctor's advice.Do not use Compazine before breast-feeding without doctor's permission.

Contraindications

Compazine is not allowed to people who are hypersensitive to any components of this drug. Contraindicated in people with severe toxic CNS depression, coma, subcortical brain damage, bone marrow depression,severe liver or cardiac disease, narrow-angle glaucoma, pediatric surgery.



Possible side effect

They may include call types of an allergic reaction. Also the most possible side effects include:

twitching or uncontrollable movements of your eyes, tongue, lips, face, arms, or legs;

tremor, drooling, trouble swallowing, problems with balance or walking;

feeling restless, jittery, or agitated;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;

feeling like you might pass out;

seizure (black-out or convulsions);

decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;

nausea and stomach pain, skin rash, and jaundice (yellowing of the skin or eyes);

pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms;

urinating less than usual or not at all;

joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color;

slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious include:

dizziness, drowsiness, anxiety;

sleep problems (insomnia), strange dreams;

dry mouth, stuffy nose;

blurred vision;

constipation;

breast swelling or discharge;

a missed menstrual period;weight gain, swelling in your hands or feet;

impotence, trouble having an orgasm;

mild itching or skin rash;

headache.

If you experience one of them stop using Compazine and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.



Drug interaction

Also note that interaction between two medications does not always mean that you

must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.



Overdose

Sympotms of Compazine overdose may include dry mouth, constipation, bloating or stomach cramps, extreme drowsiness or feeling restless and agitated, changes in heart rate, fever, and fainting. If you experience one of them or any unusual symptoms call your doctor immediately.



Storage

Store at room temperature between 20-25 C (68-77 F).



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Clinical Verification

Last Clinically Updated: August 15, 2026

Written By

Dr. Elena Vance, PharmD

Clinical Specialist in Neuropharmacology

Fact Checked By

Marcus Thorne, MS

Biomedical Data & FDA Label Verification

Medically Reviewed By

Dr. Arthur Campbell, MD

Board-Certified Psychiatrist (ABPN)