Generic Dymista

Common use

Dymista combines azelastine, an antihistamine, and fluticasone, a corticosteroid, to provide relief from nasal symptoms of seasonal allergic rhinitis. It works by blocking histamine action and reducing inflammation in the nasal passages.

Dosage and direction

Dymista is usually administered as 1–2 sprays in each nostril twice daily, or as directed by your healthcare provider. Gently blow your nose before use, and tilt your head slightly forward while spraying. Do not exceed the recommended dose.

Precautions

Inform your doctor if you have glaucoma, cataracts, infections in the nose or throat, or a history of nasal surgery. Avoid exposure to airborne infections while using the spray. Monitor for persistent nosebleeds or irritation.

Contraindications

Do not use Dymista if allergic to azelastine, fluticasone, or any component of the nasal spray.

Possible side effect

Common side effects include nasal irritation, bitter taste, headache, and mild nosebleeds. Rare but serious side effects may include severe allergic reactions, vision changes, or signs of infection. Seek medical attention if severe symptoms occur.

Drug interaction

Dymista may interact with other nasal corticosteroids or medications affecting the immune system. Inform your doctor about all prescription drugs, over-the-counter products, and supplements you are taking.

Missed dose

If a dose is missed, administer it as soon as you remember. Do not double the dose to make up for a missed one.

Overdose

Overdose may cause excessive nasal irritation or systemic corticosteroid effects. Seek medical attention if overdose is suspected.

Storage

Store Dymista at room temperature, away from heat, moisture, and light. Keep the bottle tightly closed and out of reach of children.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Clinical Verification

Last Clinically Updated: August 15, 2026

Written By

Dr. Elena Vance, PharmD

Clinical Specialist in Neuropharmacology

Fact Checked By

Marcus Thorne, MS

Biomedical Data & FDA Label Verification

Medically Reviewed By

Dr. Arthur Campbell, MD

Board-Certified Psychiatrist (ABPN)