Generic Glyxambi

Common Use
Glyxambi is prescribed for adults with type 2 diabetes whose blood sugar is not adequately controlled by diet and exercise alone. It helps lower blood glucose by promoting glucose excretion through urine and enhancing the body’s natural insulin response. Maintaining proper blood sugar levels reduces the risk of diabetes-related complications.

Dosage and Direction
The recommended dose is one tablet taken orally once daily, with or without food, or as directed by a healthcare provider. Swallow the tablet whole with water and take it at the same time each day. Do not change the dose without consulting your doctor.

Precautions
Before using Glyxambi, inform your doctor if you have kidney or liver disease, low blood pressure, or a history of urinary tract infections. Monitor blood sugar regularly and stay hydrated to avoid dehydration. Avoid driving or operating machinery if you experience dizziness or low blood sugar.

Contraindications
Glyxambi should not be used in patients with type 1 diabetes, diabetic ketoacidosis, severe kidney impairment, or known hypersensitivity to empagliflozin, linagliptin, or any component of the tablet.

Possible Side Effects
Common side effects include urinary tract infections, hypoglycemia (especially when combined with insulin), headache, and nasopharyngitis. Rare but serious effects may include dehydration, kidney problems, or ketoacidosis. Seek medical attention if severe symptoms occur.

Drug Interaction
Glyxambi may interact with insulin, sulfonylureas, diuretics, or other medications affecting kidney function or blood sugar. These interactions can increase the risk of hypoglycemia or dehydration. Inform your healthcare provider about all medications and supplements you are taking.

Missed Dose
If a dose is missed, take it as soon as you remember. If it is close to the time of the next dose, skip the missed dose. Do not take a double dose to make up for a missed one.

Overdose
Overdose may cause severe hypoglycemia, dehydration, or kidney problems. Seek immediate medical attention if an overdose is suspected.

Storage
Store Glyxambi tablets at room temperature, away from heat, moisture, and direct sunlight. Keep out of reach of children. Do not use after the expiration date.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Clinical Verification

Last Clinically Updated: August 15, 2026

Written By

Dr. Elena Vance, PharmD

Clinical Specialist in Neuropharmacology

Fact Checked By

Marcus Thorne, MS

Biomedical Data & FDA Label Verification

Medically Reviewed By

Dr. Arthur Campbell, MD

Board-Certified Psychiatrist (ABPN)