Generic Lisinopril

Common use

Lisinopril is used to treat high blood pressure (hypertension) in adults and children 6 years and older, including renovascular, acute myocardial infarction in clinically stable condition of the patients, heart failure (adjuvant treatment), diabetic nephropathy. The principle of this drug is to relax blood vessels, causing them to expand, it can lead to prevention of occurrence of strokes, heart attacks and kidney problems. Lisinopril is also used after acute myocardial recovery, and is used with other drugs (eg, "water pills" / diuretics, digoxin) to treat heart failure. This drug belongs to a class of medications called ACE inhibitors.



Dosage and direction

Take medicine for adults 1 time per day. The dose is determined individually, depending on the evidence, the state of renal function and concomitant therapy. Typically, the initial dose is 2,5-5 mg, the average maintenance dose - 5-20 mg, the maximum daily - 80 mg.



Precautions

Treatment is carried out under regular medical supervision (water-electrolyte balance). During treatment requires monitoring of blood pressure, protein level and plasma potassium, urea nitrogen, creatinine, renal function, blood picture, body weight and dieting. You have to be careful during surgery (including dental), especially when using general anesthetics that have a hypotensive effect.



Contraindications

Hypersensitivity, pregnancy, breast-feeding.



Possible side effects

You can feel headache, dizziness, nervousness, fainting, drowsiness, insomnia, tremors, convulsions, visual disturbances, palpitations, chest pain, hypotension, arrhythmia, dry cough and malignant tumors of the lung, hemoptysis, pain when breathing, bronchitis, dry mouth, indigestion, heartburn, vomiting, diarrhea / constipation, bloating, abdominal pain, renal failure, weakening of libido, impotence, arthritis, neck pain, back pain, rash, urticaria, and syndrome of Stevens - Johnson.



Drug interactions

List of the drugs that can interact with Lisinopril: gold injections to treat arthritis, lithium (Lithobid, Eskalith), a potassium supplement such as K-Dur, Klor-Con, salt substitutes that contain potassium, insulin or diabetes medication you take by mouth, aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), naproxen (Aleve, Naprosyn), and others, or a diuretic (water pill).



Missed dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.



Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Lisinopril overdose symptoms may include feeling extremely dizzy or light-headed, or fainting.



Storage

Store Lisinopril at room temperature away from moisture and heat.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Clinical Verification

Last Clinically Updated: August 15, 2026

Written By

Dr. Elena Vance, PharmD

Clinical Specialist in Neuropharmacology

Fact Checked By

Marcus Thorne, MS

Biomedical Data & FDA Label Verification

Medically Reviewed By

Dr. Arthur Campbell, MD

Board-Certified Psychiatrist (ABPN)