Generic Loxitane

Common use

Loxitane belongs to a class of medications so called tricyclic antipsycotics. It is not know exactly how this medication works. It is used to treat schizophrenia.



Dosage and directions



Precautions

Tell you doctor about all conditions you have and especially: if you have any allergies, you have a history of other mental problems, heart problems, glaucoma, difficulty urinating or risk factors for difficult urination, Parkinson disease, breast cancer, liver problems, brain growths or cancer, a stomach blockage, or seizures; you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement; you are pregnant, planning to become pregnant, or are breast-feeding; you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement; you are dependent on alcohol or drink large amounts of alcohol regularly; you are very ill or weakened.



Contraidications

You should not use Loxitane if you have allergy to it or to other similar medications; you take sodium oxybate, you have severe central nervous system depression, you are in coma or have been sedated.



Possible side effects

The most common side effects are constipation, blurred vision, dizziness, drowsiness, dry mouth, headache, nausea, stuffy nose, trouble sleeping, omiting, weight gain or loss.

Severe side effects incude Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; altered mental abilities, including lack of response to your surroundings; chills or persistent sore throat; confusion; dark urine; decreased urination; fainting or faintness; fast or irregular heartbeat; hyperactivity; increased saliva production; increased thirst; involuntary, uncontrolled muscle movements; menstrual changes; mental or mood changes; muscle twitching; numbness or tingling of the skin; restlessness; seizures; shortness of breath; severe constipation; slurred speech; staggering or shuffling gait; stiff or rigid muscles; sweating; tremor; unexplained fever; vision changes; yellowing of the eyes or skin.

Seek medical attention if one of the listed above symptoms occurs.



Drug interaction

Tell your doctor if you take the folllowing medicines:

barbiturates (eg, phenobarbital), narcotics (eg, codeine), or sodium oxybate ( GHB) because the risk of side effects, such as severe drowsiness, may be increased ;anticholinergics (eg, trihexyphenidyl) because side effects of Loxitane may be increased; benzodiazepines (eg, lorazepam) because side effects may be increased by Loxitane.

Missed dose

If you miss a dose of Loxitane, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.



Overdose

Symptoms of overdose include decreased urination; difficulty breathing; involuntary, uncontrolled muscle movements; loss of consciousness; seizures; severe or persistent dizziness. Seek medical attention immediately if you overdosed the medicine.





Storage

Store Loxitane at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Loxitane out of the reach of children and away from pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Clinical Verification

Last Clinically Updated: August 15, 2026

Written By

Dr. Elena Vance, PharmD

Clinical Specialist in Neuropharmacology

Fact Checked By

Marcus Thorne, MS

Biomedical Data & FDA Label Verification

Medically Reviewed By

Dr. Arthur Campbell, MD

Board-Certified Psychiatrist (ABPN)