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Generic Prednisolone
Prednisolone

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This medication is used to treat a variety of medical conditions. It is often used to treat conditions that cause swelling, redness, itching, or discomfort in the nose. This medication is used to treat conditions like seasonal allergic rhinitis, nonallergic rhinitis, and vasomotor rhinitis.

 

Prednisolone belongs to a class of drugs called glucocorticoids. Glucocorticoids work by suppressing the immune system. This helps prevent inflammation and swelling in the nose. When this condition occurs, patients experience watery eyes, sneezing, runny nose, and nasal congestion.

 

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Product Description

Prednisolone is a steroid that's used to treat inflammation of the digestive tract and skin. It's also prescribed for other conditions like swelling in the hands and feet, allergies, asthma, and certain types of arthritis. The complex between the hormone and the receptor penetrates into the nucleus of the target skin cell enhancing the expression of the genes that code the synthesis of lipokortins, the substances which inhibit phospholipase A2 and reduce the synthesis of metabolic products of arachidonic acid cyclic known to take part in inflammatory reaction.

 

Uses

 

Prednisolone is the oldest synthetic corticosteroid drug, and it has been used widely to treat many conditions including bronchial asthma, inflammation of the joints, certain types of rheumatism and lupus erythematosus, as well as to treat allergies and various autoimmune diseases, acute gouty arthritis, rheumatoid arthritis, and polymyalgia rheumatic.

 

In fact, this type of medication is the most commonly prescribed drug in the United States.

 

Benefits

 

Prednisolone is beneficial for its ability to reduce pain and swelling in joints and bones and help with joint replacement surgery. It also helps to reduce the size of swollen, red, painful, and warm areas of the skin. It can reduce a person’s chances of having a heart attack, stroke, and cancer. The drug can also be useful for people with lupus and asthma.

 

Efficacy

 

The oral form of the drug is effective for treating rheumatoid arthritis. There is evidence that it works better than other similar medications. It is likely to cause weight gain and water retention. It may take up to two weeks for the full benefits to be realized. In some people, it takes longer.

 

Prednisolone is taken orally, and it reaches its maximum concentration in the blood in 4-6 hours. The half-life of prednisolone is about 14 hours. The blood levels of prednisolone are affected by the time of the last dose. The highest concentrations occur within 12 hours after a dose. The half-life decreases when the dose is repeated every 8 hours or the patient is on a high dose.

 

Mechanism of Action

 

It blocks the effects of two chemicals in the body called cytokines that are involved in producing an inflammatory response. Cytokines are like chemical messengers that tell your body to release cells to fight infection, inflammation, and other disease processes.

 

The active ingredient in prednisolone works by blocking the activity of the enzyme known as phospholipase A2. This enzyme is found in the cell membrane, where it handles the breakdown of the fatty acids in the cell membranes to form various chemicals that are needed by the body.

 

Dosage

 

The usual dose of prednisolone is 10 mg per day. If the patient experiences any adverse effects, the dose can be decreased to 5 mg/day or 2.5 mg/day.

 

Overdose

 

A person may overdose by taking more than the recommended dose of this medication. Overdose of this type of medication can lead to a condition known as Cushing's syndrome, and high blood pressure.

In overdose, prednisolone can have toxic effects. They can affect your liver, heart, bones, brain, and kidneys.

 

Missed Dose

 

We recommend that you take your regular dose on schedule even if you feel well and there are no signs of infection. It is important that you take prednisolone for the full course of treatment and that you do not stop taking it until your doctor tells you it is time for the next dose.

 

If you forget to take a dose or miss a dose, take it as soon as you remember.

 

If it is almost time for your next dose, wait until then to take the next one. Do not take two doses at once.

 

Dosage Forms & Strengths

 

Prednisolone is available in several strengths and forms: Tablets, Oral Solution, Cream, Ointment, Liquid Syrup, Injection, Topical Ointments, and Vaginal Gel.

 

It comes in strengths of 5 mg, 10 mg, 20 mg, 30 mg, 40 mg, and 50 mg.

 

Side Effects

 

Although prednisolone is very effective in reducing inflammation and pain associated with a wide range of inflammatory disorders, it can also cause undesirable side effects. Some of these unwanted effects include acne or hives, weight gain, facial hair growth, insomnia, dizziness, diarrhea, constipation, vomiting, blurred vision, changes in mood, and muscle and joint aches.

 

Contraindications

 

There are some conditions that may make the use of this medication unsafe. We do not recommend it for people with the following conditions:

 

- If they have diabetes mellitus because it may worsen their condition.

 

- If they have an infection of the bones, joints, heart, blood vessels, lungs, liver, or brain.

 

- If they have a high fever.

 

- If they have a bleeding disorder, such as hemophilia, they may bleed more easily.

 

- If they have had an organ transplant.

 

- If they are taking a drug for HIV infection.

 

If you take prednisolone with alcohol, your risk of side effects increases. 

 

Warnings

 

The drug may cause weight gain and water retention, which can lead to high blood pressure and diabetes.

 

Tell your doctor if you are pregnant or breastfeeding before using prednisolone. Avoid alcohol while taking this drug. Do not give this medication to an infant younger than six months old.

 

Precautions

 

You should avoid giving the Prednisolone to a child under two years old. Children's Use of this medication in children has not been studied well, but it is probably not as safe as in adults. Children should be treated with the lowest dose of medication that is likely to work well for them.

 

Drug-Drug Interactions

 

If you take any medications that contain prednisolone, you may need to change some other medications you take. This is because when the body absorbs prednisolone, it affects how other medications are absorbed, and vice versa. Examples include:

 

- The absorption of oral contraceptive pills may be reduced.

 

- Drugs that may increase blood pressure (such as certain diuretics) may make it harder for your blood vessels to relax and may increase your risk of side effects.

 

- Estrogen-containing medications such as birth control pills and certain oral contraceptives; antifungals such as itraconazole; rifamycins such as rifabutin; St. John's wort; and seizure medications such as phenytoin.

 

To prevent problems, talk to your doctor about taking prednisolone before taking any prescription or over-the-counter medication.

 

Storage

 

Store the medication at room temperature between 20C and 25C away from moisture and heat sources. Store it in a light-resistant container. Keep it out of the reach of children and pets. 

 

Generics

 

Alternatives

If you are looking for alternatives to Prednisolone, consider the following medications that are used to treat the same symptoms as prednisolone: dexamethasone, Meloxicam, betamethasone, methotrexate, Arava, and Mometasone.

 

Patient Reviews

 

Most reviews state that Prednisolone is effective in the healing of acute cases but the drug has unwanted actions on a long-term basis and may cause side effects. Patients have complained about the following adverse reactions. It may increase the risk of developing osteoporosis in the long term. It may increase the risk of heart attacks, strokes, blood clots, high blood pressure, diabetes, cataracts, skin problems, and weight gain. It may cause headaches, insomnia, stomachache, vomiting, or diarrhea. Some patients have reported that it may cause depression, irritability, and mood swings. Patients have also reported that it can cause dry mouth and taste changes. It may cause facial flushing or acne. It may cause hair growth, hair loss, or hives. It may cause drowsiness or dizziness.

 

The following patient reviews are the opinions of actual patients who have taken this medication. These patients did not provide their identities, but they do offer a valid perspective on the experience of using prednisolone.

 

"I use this drug as a daily part of my routine. I have had it for many years. It helps with inflammation of the eye and helps with swelling of the eye and sinuses. My doctor prescribes this medication for me and it has helped me to get rid of some of the inflammation in my eyes." M.A.

 

"I am a diabetic, and I take this medication when I have to have eye surgery. My eyes were inflamed and I couldn't have surgery without it. After the surgery, my vision was fine." J.F.

 

FAQ

 

How to Take Prednisolone?

 

Definitely follow your physician's advice about dose, schedule, and any other medication you are taking. It is important that you know what medications you are taking so that you don't accidentally take too much or get sick.  

 

Take the prescribed dose. Do not stop taking this medicine without talking to your doctor first. Stopping this drug suddenly may cause side effects.

 

Take Prednisolone with or without food?

 

The best time to take the drug is at bedtime. Take it on an empty stomach if possible, but do not eat or drink for at least two hours before taking it.

 

How long does Prednisolone take to work and show effect?

 

In short, it can take up to three hours for Prednisolone to work and for symptoms to work. Prednisolone may be effective for 2-3 days before symptoms improve. If you are still experiencing symptoms after that, talk to your doctor. Your doctor will monitor you carefully, especially if you are taking this drug for a prolonged period. Maybe you need a different dose of prednisolone.

 

What should I avoid while taking Prednisolone?

 

Some of the side effects may not affect everyone. It is important that you read the side effects list to see what side effects you might experience and what precautions you should take. In addition, always tell your doctor about any other medications or supplements you are using. Some of these drugs may interact with each other or with Prednisolone, causing unwanted effects. You should avoid drinking alcohol while taking Prednisolone. It may cause you to become very sleepy and tired. It may also make you more likely to feel dizzy or have stomach pain.

 

Can I take Prednisolone and drink alcohol?

 

First, talk to your physician about this because Prednisolone may affect the way you drink alcohol. Alcohol can increase the risk of side effects such as dry mouth, headache, heartburn, dizziness, and fainting. Second, Prednisolone will worsen some of the side effects of alcohol.

 

The combination can also lead to a greater chance of liver problems.

 

Can I drive a vehicle after consuming Prednisolone?

 

Yes, but you have to be cautious as it is a potent drug and can cause side effects like drowsiness, headaches, and insomnia. You must be careful about driving a vehicle while on Prednisolone as it may affect your ability to react in an emergency.

 

Is Prednisolone safe to take during pregnancy and breastfeeding?

 

Pregnant women should avoid using prednisolone because there are possible risks to the fetus. Prednisolone is not usually recommended for pregnant women and may be avoided during pregnancy unless absolutely necessary.

 

Breastfeeding Women who are breastfeeding should avoid taking prednisolone because of the risk of the medication passing into breast milk.

 

Does Prednisolone have an FDA Black-box warning?

 

Yes, as Prednisolone may cause severe side effects in some patients, including sudden death and loss of vision in case of injection in the epidural space.

 

How much does Prednisolone cost?

 

When you buy in bulk, it's cheap and costs around $0.5 per pill. With an online pharmacy, you can order many pills at once and save money.

 

Where can you buy Prednisolone online safely?

 

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Do I need a prescription to buy Prednisolone online?

 

The prescription may be required because of the strength of the medicine. The need for a prescription depends on your location and how you are buying prednisolone. If you are in the US, you will need to have a prescription from your doctor or health care provider to buy prednisolone online. But you can buy prednisolone online from an international online pharmacy without a prescription, as long as it's for pet or personal use.

 

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