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Generic Remeron (Mirtazapine)

Remeron is used for treating symptoms of depression such as sadness, loss of interest in life, or trouble sleeping. Remeron may also be used for purposes not listed in this medication guide.

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Product Description


What are the benefits of taking this medication?


- It is used to treat insomnia and relieve its associated symptoms.


- It can help people with a certain kind of depression called major depressive disorder (MDD). This type of depression includes feeling helpless, hopeless, and guilty for a long period or time. Sometimes those who take remeron for sleep feel so sleepy day after day that it becomes impossible to function either at work or socially with their family and friends.


What should I know before taking remeron for sleep?


-Receiving medical advice from your doctor before using this drug is essential since some medications may react badly to remeron side effects. There have also been reports of people abusing the drug to achieve a high, this may lead to addiction.


- Although remeron is indicated for insomnia and depression, it should not be used as an alternative medication for treatment of schizophrenia or bipolar disorder. It gives excessive drowsiness to the person who takes it compared with other types of sleep medications like Ambien which sometimes makes people have broken to sleep with vivid dreaming and then they may feel groggy the following day.


- As per FDA warning, if you are pregnant or breast feeding you should avoid this drug since it is untested in children. It could also be harmful for infants whose mothers were taking remeron during pregnancy.


- If you have any heart problems or narrow-angle glaucoma you should ask your doctor before taking remeron for sleep.


- Since the drug contains lactose, it is advised that people with lactose intolerance avoid this medication to prevent any possible life threatening reactions.

How does remeron work and what are its side effects?


- This drug belongs to a class of medications called sedative-hypnotic agents. These drugs affect chemicals in the brain that may become unbalanced and cause sleep disorders like insomnia. They can also alter moods which can lead to depression, bipolar disorder, or mania episodes in patients who suffer from these conditions.


- Some users have reported experiencing one of the following side effects of remeron:

  • drowsiness, tiredness or weakness
  • constipation
  • dry mouth
  • headache


What are the contraindications and interactions for remeron?


- Patients with cardiovascular disease, kidney or liver failure should not use this drug. If you are suffering from severe depression, please consult your doctor before taking remeron as it may lead to suicidal thoughts or actions. Persons who use alcohol while taking this drug should be careful since it increases the risk of having a fatal heart attack.


-You should avoid drinking alcohol while using this medication and never exceed the recommended dose. Reactions like becoming dizzy, lightheaded or passing out should be reported to your doctor immediately.


-The major interactions described by FDA for this drug included the following ones:


-Tramadol, an opioid pain reliever and migraine medication (e.g., Imitrex) - These drugs interact with remeron leading to increased risks of serious heart rhythm problems.


- Antidepressant drugs like: bupropion, mirtazapine, nefazodone, and venlafaxine - Combining remeron with these medications can lead to serotonin syndrome, a rare but serious drug reaction that causes symptoms such as high fever, sweating or shaking; changes in blood pressure; increased heart rate; agitation, hallucinations or coma.


- Monoamine oxidase inhibitors (MAOIs) - This drug combination increases the risk of very high blood pressure and other serious side effects.


What are the important warnings about remeron?


- The following cautionary statements have been reported as associated with this medication:


- Patients should not take remeron if they are allergic to any ingredient of the pill.


- The drug should be used with caution in patients who have severe breathing problems or those who have narrow angles or glaucoma since it can worsen these conditions and cause changes in heart rate, respiration and/or blood pressure which can lead to serious complications.


- There have been reports of seizure and other brain disorders when remeron was used for sleep problems in pregnant or breastfeeding women. Patients should ask their doctors whether the drug is safe to use if they are nursing a baby before taking it.


-Patients with severe depression may experience serious thoughts of suicide and should consult their doctor before taking remeron.


-Patients who consume alcohol while using remeron may suffer from adverse effects such as changes in vision, drowsiness and dizziness that can lead to serious injury or death if the person is operating machinery like cars or other vehicles.


What are the important things I need to know while taking this drug?


  • Patients should tell their doctors whether they are pregnant or breastfeeding. This information will help determine if it is safe to take the medicine during these times since there have been a few reports of no damage done to babies whose mothers were prescribed remeron for sleep disorders, however none of these studies was conducted on infants who had mothers with depression which could cause some risks such as suicide.


  • Patients should not use alcohol while taking this drug, especially if they are going to drive or be in machinery like a car or a train. It is possible that remeron increases the effects of alcohol and can cause serious side effects such as changes in vision, drowsiness and dizziness which can lead to injury if patients take it along with alcohol.


  • Patients will also need to make sure that there are no interactions with other medications they might be prescribed. Reactions such as confusion, hallucinations and seizures have been observed when remeron was used with bupropion (a smoking cessation medication) or mirtazapine (an antidepressant), among others.- Patients using tramadol (a pain reliever) with remeron may need to be monitored more closely for serious heart rhythm problems.


Individuals who experience any of these symptoms while taking the drug should seek immediate medical attention: fast or irregular heartbeat, seizures, severe headache and dizziness, extreme drowsiness, hallucinations or feelings like they are not real and unusual changes in behavior. These are signs that can indicate an overdose or other adverse effects.


What happens if I miss a dose?


If patients are advised by their doctor to stop using the medication because of side effects or another reason, then it is recommended that they do so immediately. They should also inform their doctors about this action since there might be special instructions regarding how much time has passed before treatment needs to be discontinued.


What happens if I overdose?


Any signs of overdose should be taken very seriously and patients should call a doctor or emergency healthcare provider immediately. Symptoms of an overdose include: nausea, vomiting, dizziness, drowsiness and chest pain. These can indicate overuse which is a dangerous effect of remeron that can lead to severe complications such as seizures or coma if left untreated.


Mirtazapine is an antidepressant that works in the brain by affecting certain chemicals, such as norepinephrine and serotonin. It helps to relieve depression by acting on nerve cells (neurons) in the brain.


For those who have decided to take mirtazapine tablets:


ReMeron (mirtazapine) is used alone or with other medications to treat depression. This medication may also be used to treat anxiety before surgery. Mirtazapine belongs to a class of drugs known as tetracyclic antidepressants . It works in the brain to block the reuptake of certain natural substances called norepinephrine and serotonin . This helps to improve mood.


The recommended dose is 15 mg once a day at bedtime. It may be increased up to 45 mg per day if needed. Higher doses are more likely to cause side effects such as drowsiness, dizziness, dry mouth ,constipation, nausea or weight gain.


remeron has not been studied in children under 18 years of age for depression or anxiety . speak with your doctor about whether this medication may be right for you. Tell your doctor right away if you start having abnormal thoughts or behavior while taking mirtazapine tablets . Tell your doctor immediately if you develop any new or unusual symptoms while taking remeron tablets, such as:


The most common side effects of remeron are drowsiness dizziness , tremor, dry mouth, constipation and weight gain. Tell your doctor if you have any side effect that bothers you or that does not go away.


Do not take more than 45 mg per day and avoid alcohol while using this medication because it may increase the risk of serious side effects . Avoid activities requiring alertness such as driving or operating hazardous machinery until you know how mirtazapine affects you . Do not drink alcohol while using this medication. Drinking alcohol with mirtazapine can cause serious unwanted effects, including increased risk of depression, thoughts of suicide and liver damage.


What special precautions should I follow?


Before you take mirtazapine tablets, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.


Before taking this medication:


  • Tell your doctor or pharmacist your medical history, especially of: diabetes , abnormal blood pressure, heart disease , high cholesterol/triglycerides, seizure disorder (epilepsy), kidney disease , recent head injury.


  • Tell your doctor if you are pregnant before starting this medication because remeron is not approved for use in women . It may harm the baby. If you use remeron while pregnant, call your doctor immediately.


  • Tell your doctor if you are breastfeeding because mirtazapine passes into breast milk and may harm a nursing infant .


What should I watch for while using this medication?


Follow your doctor's instructions concerning any restrictions on food, beverages, or activity.


  • Avoid alcohol. Do not take other medications that cause drowsiness (such as antihistamines ) without first discussing with your doctor.


  • You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient.


  • Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe .


  • You may experience blurred vision , double vision , trouble telling blue from green color as well as drooping eyelids while taking mirtazapine tablets . If this occurs, tell your doctor right away to rule out possible serious side effects such as sudden increase in eye pressure (glaucoma).


  • Do not stop taking remeron tablets without first talking to your health care provider. You could become ill with uncomfortable withdrawal symptoms because your body has become used to being on this medication . The more gradually you are weaned off the drug, the safer and less severe any withdrawal symptoms may be.


What side effects can this medication cause?


Mirtazapine tablets can cause serious unwanted side effects such as weight gain, which may lead to problems with your heart or blood pressure; liver damage; vision changes ; thoughts of hurting yourself or committing suicide (see warning section); difficulty breathing; worsening depression or loss of interest in life; increased appetite and/or frequency and urgency of urination.


If these symptoms occur, call your health care provider right away.


Some people taking mirtazapine tablet have had suicidal thoughts and actions while being treated with it for depression, anxiety, panic disorder, obsessivecompulsive disorder (ocd), posttraumatic stress disorder (ptsd) and other psychiatric problems. Even if you have no history of suicidal thoughts or actions, you should be watched closely for them while taking mirtazapine tablet .


Contact your health care provider immediately if any unusual changes in mood occur. Your family or other caregivers should also be alert to changes in your behavior that could signal distress or depression.


If this medication causes swelling of the hands, face, eyes, lips mouth , throat , arms and legs, difficulty swallowing or breathing , fast heartbeat , increased sweating , feeling faint, dizzy, or light-headedness upon standing up quickly ; contact your doctor right away.


Some people have experienced serious side effects when they stop using mirtazapine.


Tell your doctor right away if you have any of the following symptoms : headache , nausea , dizziness , vomiting ; difficulty sleeping; feeling tired or irritable .


These are not all the possible side effects of this medication. For a complete list, ask your health care provider or pharmacist .


What should I look out for in the elderly?


Elderly people are more likely to get drowsy and dizzy easily while taking remeron tablets so they should be monitored closely.


How do I store and/or throw out Remeron?


Store at room temperature ( 77 F), away from light and moisture .

  1. Do not store in the bathroom.
  2. Keep all medicines away from children and pets .
  3. Take mirtazapine tablets with a full glass of water.


What is the most important information I should know about Remeron?


The following have been reported with use of this medication:

  • Suicidal thoughts and actions (including some cases when these symptoms were unusual).


  • People who take medicines like Remeron may have a higher chance of thinking about suicide or dying.


  • Some people who had suicidal thoughts or actions while taking antidepressants for depression or other conditions thought they were "just being anxious" or having trouble sleeping. It is not known if this problem is caused by the antidepressant, another illness, or a combination of these. If you have any of the following symptoms , contact your health care provider right away : thoughts that you would be better off dead or of hurting yourself; new or worsening depression (especially if you have any of the following symptoms : sleeplessness, irritability, agitation, panic attacks); acting aggressively , being angry or violent ; acting on dangerous impulses ; thoughts of suicide or hurting yourself; feeling very agitated or restless ; an extreme increase in activity and talking (mania).


  • Do not take antidepressants like Remeron during pregnancy . If you become pregnant, stop taking remeron tablets as soon as you find out.


Discuss the risks and benefits with your health care provider. Other medications-Since certain medicines can affect how mirtazapine tablets work, it is very important to tell your health care provider about all other medicines you are taking. These include prescription or over-the-counter medicines, vitamins, and herbal supplements .


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