Generic Rulide

Common use

Rulide is a semi-synthetic macrolide antibiotic used for the treatment of mild to moderate infections of upper respiratory tract infections (acute pharyngitis, tonsillitis, sinusitis) caused by susceptible pathogens. Rulide prevents bacteria from growing, by inhibiting their protein synthesis.



Dosage and directions

Rulide is taken once or twice daily, a daily dose is 300 mg for adults.Usual course of treatment is 7-10 days.



Precautions

In patients with hepatic failure half-life of Rulide in serum increases. If liver disorders are severe (hepatic cirrhosis with jaundice and/or ascites), the dose of the medications should be corrected.

Small amounts of Rulide are excreted in human breast milk so breast feeding or treatment of the mother should be stopped if required.



Contraindications

Hypersensitivity to Rulide or macrolide antibiotics, concomitant therapy with vasoconstrictive ergotamine type medications.



Possible side effect

Most common side effects are: nausea, vomiting, diarrhea, epigastric pain, flatulence, headache, dizziness, malaises, hives, rash, swelling of tongue and face, moniliasis (candidiasis)



Drug interaction

Rulide is able to increase plasma levels of theophylline when co-administered. It also may affect activity of warfarin and erythromycin.



Missed dose

If you missed a dose take it as soon as you remember. If it almost time of your next dose just skip it and return to your regular schedule. Never double dose this medication.



Overdose

In case of serious and persistent symptoms of allergy (hives, swelling of face and tongue, rash) consult your doctor about medical attention. In general Rulide is well tolerated.



Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment

Clinical Verification

Last Clinically Updated: August 15, 2026

Written By

Dr. Elena Vance, PharmD

Clinical Specialist in Neuropharmacology

Fact Checked By

Marcus Thorne, MS

Biomedical Data & FDA Label Verification

Medically Reviewed By

Dr. Arthur Campbell, MD

Board-Certified Psychiatrist (ABPN)