Generic Tenofovir

Common Use

Tenofovir is an antiviral medication used to treat HIV-1 infection as part of combination antiretroviral therapy. It helps reduce the viral load in the body and supports immune system function. The drug is also prescribed for the treatment of chronic hepatitis B infection, improving liver health and slowing disease progression. In addition, it may be used for HIV prevention (PrEP) in individuals at increased risk.

Dosage and Direction

Tenofovir is typically taken orally once daily, with or without food, as directed by a healthcare provider. The exact dosage depends on the condition being treated and individual patient factors. For HIV treatment, it is used in combination with other antiretroviral medications. It is important to take the medication consistently at the same time each day for optimal effectiveness.

Precautions

Before starting Tenofovir, inform your healthcare provider about any existing kidney or liver conditions. Regular monitoring of kidney function and overall health is recommended during treatment. Use with caution in patients with reduced renal function or a history of bone density issues. Pregnant or breastfeeding individuals should consult a healthcare professional before use.

Contraindications

Tenofovir should not be used in patients with known hypersensitivity to the active substance or any of its components. It is contraindicated in individuals with severe kidney impairment unless specifically advised by a healthcare provider. Concurrent use with certain medications that affect kidney function may also be restricted. Always consult a doctor to ensure the medication is appropriate for your condition.

Possible Side Effects

Common side effects may include nausea, diarrhea, headache, and fatigue. Some patients may experience dizziness or mild gastrointestinal discomfort during treatment. In rare cases, more serious effects such as kidney problems or decreased bone mineral density may occur. Seek medical attention if any severe or persistent symptoms develop.

Drug Interaction

Tenofovir may interact with medications that affect kidney function, increasing the risk of side effects. Caution is advised when used alongside other antiviral or nephrotoxic drugs. It may also interact with certain supplements or over-the-counter medications. Always inform your healthcare provider about all substances you are taking.

Missed Dose

If a dose is missed, take it as soon as you remember. If it is close to the time of the next dose, skip the missed dose and continue your regular schedule. Do not take a double dose to make up for the missed one. Maintaining consistent dosing is important for treatment effectiveness.

Overdose

In case of overdose, seek immediate medical attention or contact a healthcare professional. Symptoms may include increased side effects such as nausea, dizziness, or kidney-related issues. Supportive care and monitoring may be required. Always follow prescribed dosing instructions to avoid overdose risk.

Storage

Store Tenofovir at room temperature, away from moisture and direct sunlight. Keep the medication in its original packaging to protect it from environmental exposure. Ensure it is kept out of reach of children and pets. Do not use the medication after the expiration date indicated on the package.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Clinical Verification

Last Clinically Updated: August 15, 2026

Written By

Dr. Elena Vance, PharmD

Clinical Specialist in Neuropharmacology

Fact Checked By

Marcus Thorne, MS

Biomedical Data & FDA Label Verification

Medically Reviewed By

Dr. Arthur Campbell, MD

Board-Certified Psychiatrist (ABPN)