Generic Zyloprim

Common use

Zyloprim is a xanthine oxidase inhibitor which used to treat gout or kidney stones, and to decrease levels of uric acid in people who are receiving cancer treatment. Zyloprim reduces uric acid production in the body, it help to prevent crystals from forming.



Dosage and direction

Take it orally once daily, probably after a meal. When you take Zyloprim you have to drink eight glasses of any liquids per day.

Commonly use dose of Zyloprin is 200 to 300 milligrams taken once daily. It can be various from weight of patients, their age or type of symptoms.

Dosage for children 6 to 10 years of age is 300 mg daily for the management of uric acid levels in certain types of cancer.

For children under 6 years of age the commonly used dose is 150 mg daily.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.



Precautions

Use with cautions if your medical history include: kidney or liver disease. Limit intake of vitamin C supplements or fruit juice while taking Zyloprim, because it may increase your chance of developing kidney stones. Relafen may cause drowsiness, so use caution activities such as driving or using machinery. Limit alcohol intake. Zyloprim should not be used during pregnancy, becoming pregnant or lactating without doctor's advice. Do not use Zyloprim before breast-feeding without doctor's advice.



Contraindications

Zyloprim is not allowed in people who are hypersensitive to any components of this medicine.



Possible side effect

They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include:

the first sign of any skin rash, no matter how mild;

pain or bleeding when you urinate;

urinating less than usual or not at all;

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;

bruising, severe tingling, numbness, pain, muscle weakness;

easy bruising or bleeding, unusual weakness;

fever, chills, body aches, flu symptoms;

jaundice (yellowing of the skin or eyes);

seizure (convulsions).

Less serious include:

nausea, vomiting, diarrhea;

dizziness or drowsiness;

increased sweating;

joint pain.If you experience one of them stop using Zyloprim and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.



Drug interaction

Zyloprim interact with the following drugs:

azathioprine (Imuran);

chlorpropamide (Diabinese);

cyclosporine (Gengraf, Sandimmune, Neoral);

mercaptopurine (Purinethol);

an antibiotic such as ampicillin (Principen, Omnipen, others) or amoxicillin (Amoxil, Augmentin, Trimox, Wymox);

a blood thinner such as dicoumarol or warfarin (Coumadin);

a diuretic (water pill).

Also note that interaction between two medications does not always mean that you

must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.



Overdose

Symptoms of Zyloprim overdose are not known well and not danger for your life. If you experience one of them or any of unusual symptoms call your doctor immediately.



Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Clinical Verification

Last Clinically Updated: August 15, 2026

Written By

Dr. Elena Vance, PharmD

Clinical Specialist in Neuropharmacology

Fact Checked By

Marcus Thorne, MS

Biomedical Data & FDA Label Verification

Medically Reviewed By

Dr. Arthur Campbell, MD

Board-Certified Psychiatrist (ABPN)